НАСЛЕДСТВЕННЫЕ БОЛЕЗНИ
ТЕРАПИЯ
G
G PROTEIN-COUPLED RECEPTORS
MUTATIONS
Mechanisms, Pathophysiology and Potential Therapeutic Approaches
GASTRULATION
SINGLE-CELL RESOLUTIONSINGLE-CELL RESOLUTION
Multi-omics profiling of mouse gastrulation at single-cell resolution
GASTROINTESTINAL TUMORS
COMBINING THERAPY
Nanoparticles Combining Gene Therapy and Chemotherapy as a Treatment for Gastrointestinal Tumors
neuronopathic GAUCHER DISEASE
GENE THERAPIES
Fetal gene therapy for neurodegenerative disease of infants
Top Five Gene Therapy Stories of 2019
Principles of and strategies for germline gene therapy
CRISPR/Cas precise genome editing technology for gene therapy and crop improvement
From preclinical development to clinical application
Gene therapy from Brazil, South Africa, and India
Four Success Stories in Gene Therapy
Twisted DNA Increases CRISPR Off-target Effects
THERAPIES
Advancements in Viral Gene Therapy for Gaucher Disease
GENE CORRECTION
DONOR-FREE CORRECTION
Gene correction by targeted interhomolog recombination
GENE EDITION
OPTIMIZED CRISPR-Cas9 COMPONENTS
Integrating gene delivery and gene-editing technologies
CRISPR/Cas-Dependent and Nuclease-Free In Vivo Therapeutic Gene Editing
Human Genome Editing: What Are the Rules?
CRISPR-Stop Codon Read Through method to control Cas9 expression for gene editing
Next-Generation Tools for Gene Editin
Avoiding Gene Editing’s Unintended Consequences
GENE THERAPY
ANTISENSE OLIGONUCLEOTIDES
Antisense oligonucleotides and other genetic therapies
GENOTOXIC EFFECTS
Genotoxic Effects of Base and Prime Editing
PROGRAMMABLE SYNTHETIC RECEPTORS
Programmable synthetic receptors: the next-generation of cell and gene therapies
gRNA
Selection of extended CRISPR RNAs with enhanced targeting and specificity
TRIALS
Record number of gene-therapy trials, despite setbacks
DURABILITY OF TRANSGENE EXPRESSION
Durability of transgene expression after rAAV gene therapy
GENE THERAPY SUICIDE
APPROACHES
Origins of Suicide Gene Therapy
DELIVERY
In vivo methods for acute modulation of gene expression in the central nervous system
A Universal GSH-Responsive Nanoplatform for the Delivery of DNA, mRNA, and Cas9/sgRNA
Ophthalmic Administration of a DNA Plasmid Harboring the Murine Tph2 Gene
Cyclodextrins in drug delivery
Cyclodextrins in drug delivery
New methods for effective transport of large genes in gene therapy
GENE EDITING
CRISPR-cas gene-editing as plausible treatment of neuromuscular and nucleotide-repeat-expansion diseases
GENE THERAPY FETAL
Gene and Stem Cell Therapies for Fetal Care
EX VIVO
Genetic diseases and leukemia
Gene therapy with transposons
IN HUMANs
CRISPR Genome Editing and Gene Therapy HIV
IN UTERO
In Utero Gene Therapy and Genome Editing
PROGRESS, PROBLEMS, VIRAL VECTORS
Advances
in pigs using CRISPR-Cas9
Gene Therapy With Regulatory T Cells
CRISPR/Cas9: A revolution in genetic disease treatment
Knockdown of Human AMPK Using the CRISPR/Cas9 Genome-Editing
CRISPR Keeps Things Fresh: Next-Generation Tools for Gene Editing
Next-Generation Tools for Gene Editing
Gene Therapy in ALS and SMA: Advances, Challenges and Perspectives
GENE REPAIR
DEVELOPMENT AND REGULATION
Advances
GLAUCOMA
DRUG THERAPIES
in situ-forming, nanoparticle-laden hydrogel for ocular drug delivery of cannabigerolic acid.
GENE THERAPY
Gene Therapy for Glaucoma by Ciliary Body Aquaporin 1
The concept of gene therapy for glaucoma the dream that has not come true yet
GLIOBLASTOMA
GENE THERAPIES
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Blood-brain barrier–penetrating single CRISPR-Cas9 nanocapsules for glioblastoma gene therapy
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CRISPR/Cas9 генотерапия; CRISPR/Cas9-Mediated Gene Therapy for Glioblastoma
TARGETED THERAPIES
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methods for delivering antiangiogenic factors
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Novel therapeutic targets
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Adeno-associated virus (AAV)-based gene therapy
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CRISPR/Cas9 Gene-Editing in Glioma Studies
GLIOMAS
TARGETED THERAPIES
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Chek-Mate for Gliomas.New research may make immunotherapy possible for hard-to-treat brain tumors
GLOMERULAR INJURY
GENE THERAPIES
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Systemic gene therapy with thymosin β4 alleviates glomerular injury in mice
GLYCOGEN STORAGE DISEASES TYPE I и TYPE III
GENE THERAPY
Gene Therapy for the Treatment of Glycogen Storage Diseases
GLIOMA MALIGNANT
NOVEL TARGETED THERAPIES
Inhibition of growth and invasivness
GLYCOMICS
NEW AND IMPROVED THERAPEUTICS
Glycan structures
GLYCOMS DEFECTS
Human
Glioblastome multiforme
Gliomas
Gorlins (Basal cell naevus) synd.
GOLD NANOPARTICLE
GENE THERAPY
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Gold Nanoparticle-Mediated Gene Therapy